Published March 2021 https://pubmed.ncbi.nlm.nih.gov/33300138/ This is a very large study with 2,021,371 participants. It looked at patients who were prescribed an opioid for pain and examined how many people continued to take them long-term (addiction) (3.17%) and how many experienced an opioid overdose (0.055%). It’s… Read More »Study: Initial opioid prescription patterns and the risk of ongoing use and adverse outcomes
Opioids for chronic pain
Misinterpretation of the “Overdose Crisis” Continues to Fuel Misunderstanding of the Role of Prescription Opioids
The study demonstrates that most overdoses are due to polypharmacy, not due to opioids alone and the numbers of ‘opioid’ induced deaths are inflated by including all deaths where opioids were found on toxicology, but may not have been the cause of death.:
Many current assumptions about opioid analgesics are ill-founded. Illicit fentanyl and heroin, not opioid prescribing, now fuel the current opioid overdose epidemic. National discussion has often neglected the potentially devastating effects of uncontrolled chronic pain. Opioid analgesic prescribing and related overdoses are in decline, at great cost to patients with pain who have benefited or may benefit from, but cannot access, opioid analgesic therapy.
Study: Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrolment randomized withdrawal trials
This meta-analysis of FDA-required double-blind, randomized, placebo-controlled clinical trials of opioid analgesics for the treatment of chronic pain has shown that there is an ample evidence base supporting the efficacy of opioid analgesics for at least 3 months’ duration, a standard period for the evaluation of treatments for chronic pain and other chronic disorders
Study: Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial
This study came in through my notifications today, but it was published two weeks ago on Clinical Pain Advisor. I also remember seeing this study being discussed on social media and online forums a few weeks ago. I meant to write it up then, but… Read More »Study: Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial
This is important for every Australian who is on long-term opioid therapy for chronic pain https://www.opioiddeprescribingguideline.com Most people in the chronic pain community will not be aware that there are Draft Opioid Deprescribing Guidelines currently open for public comment. The Draft Guidelines and a template… Read More »GUIDELINE FOR DEPRESCRIBING OPIOID ANALGESICS
Study: “One Size Fits All” Doesn’t Fit When It Comes to Long-Term Opioid Use for People with Chronic Pain
M. E. Lynch &J. KatzPublished online: 04 May 2017 Information courtesy of Kev James, Chronic Pain Patient Advocate. LinkedIn Source: https://www.tandfonline.com/doi/full/10.1080/24740527.2017.1319733 This study pulls no punches: “The use of opioids in chronic non-cancer pain continues to be a flashpoint in medicine. The media and others… Read More »Study: “One Size Fits All” Doesn’t Fit When It Comes to Long-Term Opioid Use for People with Chronic Pain
Harald Breivik First published: 09 January 2012 Information courtesy of Kev James, Chronic Pain Patient Advocate. LinkedIn Read the full study here In 2012 a group of distinguished pain clinicians from nine European countries got together to discuss the appropriate use of strong opioids for… Read More »Study: Appropriate and responsible use of opioids in chronic non-cancer pain
Study: Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry study
After three months of treatment, the large majority of patients, who were on stable doses, the average pain intensity scores were unchanged or improved for approximately 70 to 80% of patients. The most common adverse events were not serious, including constipation and nausea, and the incidence of these events declined over time on treatment.